PHARMACEUTICAL UNIT
TABLET, CAPSULES, SYRUPS, LOTION ETC.
[CODE NO.3749]
The foundation of the modern Indian pharmaceutical Industry was laid at the start of the current century when in 1901, a small factory known as the Bengal Chemical & Pharmaceutical works was established in Kolkata. Though the two world Wars gave a Phillip to the development of industry, the progress made under British rule was not significant except the British introduced into this country the allopathic system of medicine. The country depended largely for its requirements on U.K., France and Germany.
The development of Indian Drugs and pharmaceuticals Industry was not commonsurate with the size of this country and the growing needs of people, when Indian embarked on its planned economic expansion industry has been substantial and many sides with the result that it has becomes one of the leading industries. India is now producing a larger quantity of varied pharmaceuticals products. In 1948, the sale of pharmaceuticals products. In 1948, the sale of pharmaceutical products amounted to just Rs. 100 million. By 1954 the figure had rised to Rs. 540 million and by 1960 to Rs. 700 million. The figure stood at between Rs. 1500 million in 1965 and Rs. 4000 millions in 1975, Rs. 12000 millions in 1980 and above Rs. 18,500 millions presently.
The restrictions, however, continued on import of non essential patent and proprietory medicen for which suitable substitutes manufactured indigenously were available.
Prior to the launching of the second plan the manufacture of pharmaceuticals was limited largely to the processing of bulk imported drugs into tablets, capsules and other formulations. Indian firms under agreement with foreign firms are making injectables, powders ointments and liquids, and were also filling antibiotics. Certain units were producing biological extracts, vacines, and syrup. Alkalods, like quinins stry-chinea, caffeine, and morphine were also being extracted. It was however obvious that the country could not forever be dependent on foreign manufacturers for both finished drugs and basis raw materials. With the changing political climate, pharmaceutical manufacturers in India were encouraged to take up the manufacture of basis drugs wherever it was economically possible and technically feasible.
A system of collaboration was instituted, under which Indian manufacturers in association with established firms in U.S.A., Italy, U.K. began to produce a fairly comprehensive range of basic items. While the allocation of foreign exchange for the import of raw materials and basic intermediates for the production of drugs, has been more or less static the value of products manufactured has increased progressively several fold clearly indicating the growing stature, of industry and its capacity to switching over to basic raw materials and components of indigenous origin, and now the country is stated to achieve self, sufficiency in synthetic drugs of the sulpha group, anti T.B. drugs, Vitamins, and intermediates.
It has, however, been found that the present installed capacity is insufficient to meet the over growing demand of the massive population and the scope for new units to come up is substantial.
COST ESTIMATION
Land & Building (0.25 Acre) Rs. 40 Lac
Plant & Machinery Rs. 57 Lac
Working Capital for 2 Months Rs. 58 Lac
Total Capital Investment Rs. 1.66 Cr
Rate of Return 64%
Break Even Point 51%
INTRODUCTION
MARKET OVERVIEW OF PHARMACEUTICAL INDUSTRY
GLOBAL MARKET DYNAMICS & IMPLICATIONS FOR INDIA PHARMA
MULTIPLE DIGITAL AND ADVANCED ANALYTICS APPLICATIONS IN
PHARMA VALUE CHAIN
INDIA MARKET DYNAMICS & IMPLICATIONS FOR INDIA PHARMA
INCREMENTAL GROWTH IN THE INDIAN PHARMACEUTICAL MARKET
OPPORTUNITIES FOR INDIA AS A GLOBAL SUPPLY DESTINATION
INSTITUTIONALIZING QUALITY AND COMPLIANCE EXCELLENCE
BUILDING OPERATIONAL EXCELLENCE
ALTERNATE SOURCING AND SELF-SUFFICIENCY IN APIS/INTERMEDIATES
GLOBAL PHARMACEUTICAL MARKET
PESTEL ANALYSIS FOR THE PHARMACEUTICALS MARKET
PHARMACEUTICAL MARKET RESTRAINTS AND DRIVERS
THE CHANGING GEOGRAPHY OF PHARMA MARKETS
IN THE OVERALL MARKET, TOP PHARMACEUTICAL COMPANIES INCLUDE
METHODS OF RAINWATER HARVESTING
BROADLY THERE ARE TWO WAYS OF HARVESTING RAINWATER
1. SURFACE RUNOFF HARVESTING
2. ROOFTOP RAINWATER HARVESTING
ROOFTOP RAINWATER HARVESTING SYSTEM
COMPONENTS OF THE ROOFTOP RAINWATER HARVESTING
THE SYSTEM MAINLY CONSTITUTES OF FOLLOWING SUB COMPONENTS
CATCHMENTS
TRANSPORTATION
SAND GRAVEL FILTER
CHARCOAL FILTER
PVC –PIPE FILTER
SPONGE FILTER
METHODS OF ROOFTOP RAINWATER HARVESTING
A) STORAGE OF DIRECT USE
B) RECHARGING GROUNDWATER AQUIFERS
C) RECHARGING OF BORE WELLS
D) RECHARGE PITS
E) SOAKWAY OR RECHARGE SHAFTS
F) RECHARGING OF DUG WELLS
G) RECHARGE TRENCHES
H) PERCOLATION TANK
MANUFACTURER OF PHARMACEUTICAL PRODUCTS
FORMULATIONS OF TABLETS
1. TABLETS FOR FATIGUE & GENERAL TONIC
2. ANTI ASTHMATIC:-
3. COLCHICINE TABLETS
5. ANTI ALLERGIC TABLETS :
6. MULTI VITAMIN TABLETS, 500 MG EACH TABLET CONTAINS
7. ENTERO VIOFORM TABLETS:
8. TABLETS FOR COMMON COLD:
9. TABLETS FOR MENOAPUSE SYNDROMS:
10. STIMULATING TABLETS:
11. ANACIN TABLETS:
12. IRON TABLETS:
13. CAPSULES:
14. ANTI INFLAMMATORY ANTIPYRETIC AND ANALYGERIC:
15. BROAD SPECTRUM ANIT-BIOTIC CASPULES:
16. IRON WITH VITAMIN CAPSULES:-
17. ANTI ANNEMIA CAPSULES:
18. CHLORAMPHENICOL CAPSULES:
19. HEAMATINIC CAPSULES:-
20. UROBIOTIC CAPSULES:
INJECTIONS FORMULATIONS
TERRAMYCIN 1 M :-
AMPICILLIN INJECTION :-
SULPHACETAMIDE EYE-DROP :-
SULPHACETAMIDE EYE-DROP EACH ML CONTAINS:-
BETENSOL-N-EYE/EAR DROPS CONTAINS:-
SALIENT FEATURES OF FORMULATIONS OF DPHTHALMIC PREPARATIONS
OXYTOCIN INJECTION:-
OXYTOCIN -B VETC :-
MANUFACTURING PROCESS OF INJECTIONS
FILLING OF AMPOULES
FORMULATIONS OF SYRUPS
SYRUPS:
ANTI ALLERGIC COUGH SYRUP:
EDIATRIC SYRUP OF PARACETAMOL:
VICKS FORMULA 44 COUGH MIXTURE
PARACETAMOL - VITAMINIC SYRUP
MULTIVITIMAN SYRUP
COUGH SYRUP
LIQUIDS:
1. GENERAL TONIC (MULTI VITAMIN)
2. SODIUM GLYCEROPHOSPHATE
3. VITAMIN B COMPLEX WITH DIGESTIVE ENZYMES:
TONIC LIQUID:
PALATABLE POTASSIUM SUPPLEMENT:
1. EYE LOTION:
2. SKIN LOTION (FOR SPOT & PIMPLES)
3. ANTI ALLERGIC LOTION (CALAMINE LOTION)
TERRAMYCIN DENTAL PASTE:
BEPARINE CREAM:
ANTISEPTIC CREAM:
ANTI FUNGAL SKIN OINTMENT:
BURNOL OINTMENT:
FORMULATION OF OINTMENT BASES:
WASHABLE OINTMENT BASE (USED AS SCALP OINTMENT BASE)
GREASE LESS BASE: (USED IN MAKING SKIN OINTMENT)
MANUFACTURING PROCESS (TABLETS)
FLOW DIAGRAM OF TABLET MAKING PLANT
MANUFACTURE OF LIQUIDS (SYRUP)
FILTERATION:
BOTTLING:
FLOW DIAGRAM OF MIXING PLANT
CAPSULE FILLING SEALING
FILLING:
SEALING AND LOCKING:
FLOW DIAGRAM OF CAPSULE MAKING PLANT
MANUFACTURE OF LOTION
FLOW DIAGRAM OF LOTION MAKING PLANT
OINTMENT AND PASTE MAKING
FORMULATION:
MACHINERY REQUIRED
FLOW DIAGRAM FOR PASTE & OINTMENT MAKING
SUPPLIERS OF PHARMACEUTICAL PLANTS MACHINERY
SUPPLIERS OF RAW MATERIALS
GELATINE
FOOD COLOURS
SODIUM SULPHATE
PINE OIL
GLYCERINE
CAUSTIC SODA
METHYLATED SPIRIT
ASPIRIN
PARACETAMOL TABLETS (PCM)
PAPAIN POWDER
VITAMIN
THYMOL
APPENDIX – A:
01. PLANT ECONOMICS
02. LAND & BUILDING
03. PLANT AND MACHINERY
04. OTHER FIXED ASSESTS
05. FIXED CAPITAL
06. RAW MATERIAL
07. SALARY AND WAGES
08. UTILITIES AND OVERHEADS
09. TOTAL WORKING CAPITAL
10. TOTAL CAPITAL INVESTMENT
11. COST OF PRODUCTION
12. TURN OVER/ANNUM
13. BREAK EVEN POINT
14. RESOURCES FOR FINANCE
15. INSTALMENT PAYABLE IN 5 YEARS
16. DEPRECIATION CHART FOR 5 YEARS
17. PROFIT ANALYSIS FOR 5 YEARS
18. PROJECTED BALANCE SHEET FOR (5 YEARS)
