COLCHICINE AND THIOCOLCHICINE
CODE NO. 1705]
Colchicine is a medication most commonly used to treat gout. It is a toxic natural product and secondary metabolite, originally extracted from plants of the genus Colchicum (autumn crocus, Colchicum autumnale, also known as "meadow saffron").
Adverse effects are primarily gastrointestinal upset at high doses. In addition to gout, colchicine is used to treat familial Mediterranean fever, pericarditis, and Behçet's disease.
COST ESTIMATION
Plant Capacity 4.00 Kgs./day
Land & Building (1 Acre) Rs.2.35 Cr
Plant & Machinery Rs.1.15 Cr
W.C. for 1 Month Rs.2.22 Cr
Total Capital Investment Rs.6.09 Cr
Rate of Return 25%
Break Even Point 51%
INTRODUCTION
SOURCES OF COLCHICINE
PROPERTIES OF THIOCOLCHICINE
PROPERTIES & FUNCTION OF COLCHICINE
COMPOSITION, CLASSIFICATION AND LABELLING OF THIOCOLCHICINE
USES AND APPLICATION OF THIOCOLCHICINE
USES AND APPLICATION OF COLCHICINE
MARKET SURVEY
PRESENT MANUFACTURERS/SUPPLIERS OF COLCHICINE &
THIOCOLCHICINE
OCCURANCE AND PROPAGATION OF G SUPERBA
MEDICINAL APPLICATION AND ETHANOPHARMACOLOGY OF G. SUPERBA
MANUFACTURING PROCESS OF COLCHICINE AND THIOCALCHICINE
PROCESS FLOW DIAGRAM OF COLCHICINE EXTRACTION
MANUFACTURE OF THIOCOLCHICINE
PROCESS FLOW DIAGRAM FOR THE MANUFACTURE OF THIOCOLCHICINE
METHOD OF EXTRACTION AND ISOLATION OF ALKALOIDS
QUANTIFICATION OF COLCHICINE IN VARIOUS PARTS OF
GLORIOSA SUPERBA BY HPLC
ESTIMATION OF COLCHICINE IN TUBERS OF GLORIOSA SUPERBA L
COLCHICINE DERIVATIVES AND THEIR PROCESSES
SUPPLIERS OF RAW MATERIALS
SUPPLIERS OF PLANT AND MACHINERY
APPENDIX –A
01. PLANT ECONOMICS
02. LAND & BUILDING
03. PLANT AND MACHINERY
04. OTHER FIXED ASSESTS
05. FIXED CAPITAL
06. RAW MATERIAL
07. SALARY AND WAGES
08. UTILITIES AND OVERHEADS
09. TOTAL WORKING CAPITAL
10. TOTAL CAPITAL INVESTMENT
11. COST OF PRODUCTION
12. TURN OVER/ANNUM
13. BREAK EVEN POINT
14. RESOURCES FOR FINANCE
15. INSTALMENT PAYABLE IN 5 YEARS
16. DEPRECIATION CHART FOR 5 YEARS
17. PROFIT ANALYSIS FOR 5 YEARS
18. PROJECTED BALANCE SHEET FOR (5 YEARS)
