Detailed Project Report on choline chloride from ethylene oxide route (choline hydroxide and hcl)

Detailed Project Report on choline chloride from ethylene oxide route (choline hydroxide and hcl)

CHOLINE CHLORIDE FROM ETHYLENE OXIDE ROUTE

(CHOLINE HYDROXIDE AND HCL)

 [CODE NO.4172]  

Choline chloride is an essential nutrient commonly found in eggs, chicken, and number of other foods.

Applications: choline chloride is a standard component of cell culture media that serves as a phospholipid precursor for the cells.

Mechanism of action: Choline serves as a precursor component to two major cell membrane components: phosphatidylcholine and sphingomyelin. In addition, choline functions as a methyl group donor to several different substrates.

The product is generally referred to as B Complex Vitamin, which is basically poultry, feed supplement.

The product is manufactured in three steps batch process, which involves neutralization of Hydrochloric Acid with Trimethyl Amine to form Trimethyl Amine Hydrochloride. Ethylene Oxide is then added to Trimethyl Amine Hydrochloride to form Choline Chloride solution. The solution is then concentrated under vacuum to a pre determined percentage solution. Dry Choline Chloride is produced by blending in a mixer batch wise Liquid Choline Chloride with solid carriers. This blend is then fed to a Rotary Dryer where moisture is removed. This is then fed in Rotary Cooler to bring down the temperature of the mass to Atmospheric Temperature. Finally the dry choline chloride is Milled and filled in bags.

The carrier normally used is a Silica, corn Cob powder or similar absorbent powder derived from agro-waste materials. The carrier is used merely to carry the product, Choline chloride. The commercial nomenclature of the product depends upon the carrier used and the concentration of Choline. In case the carrier used is corn cob, the product is commercially called Choline Chloride Corn Cob base. If the carrier used is vegetable, it is known as Choline Chloride Vegetable base. The concentration of Choline Chloride is also usually mentioned along with the carrier used. In case the concentration is 50% Choline Chloride, it is called Choline Chloride 50% Corn Cob (or vegetable) base. The various grades of Choline Chloride are Choline Chloride on Corn Cob Carrier, Choline Chloride on Silica Carrier and Aqueous Choline Chloride.

Choline chloride is an organic compound with the formula (CH3)3NCH2CH2OH]Cl. It is bifunctional, containing both quaternary ammonium salt and an alcohol. The cation is choline, which occurs naturally. It is a white, water-soluble salt used mainly in animal feed.

In the laboratory, choline can be prepared 

by methylation of dimethylethanolamine with methyl chloride.

Industrially, it is produce by the reaction of ethylene oxide, hydrogen chloride, and trimethylamine or from the pre-formed salt:

 The principal feed resources for animal consumption in the country are crop residues like straws of wheat, rice and other cereals and stoves which are very poor in feed value. Even these ate in short supply. These are supplemented to some extent by relatively better quality fodders like cultivated leguminous and non liguminous fodder grasses and concentrates. The  latter  are formulated  largely  from agro-industrial by-product  and  forest wastes and small quantities of low-grade cereals with the present stock  of feed and fodder resources available in the country,  it is well impossible to meet the nutrient requirements of even  the present  day low-producing cattle and buffaloes such a  situation is  bound  to  aggravate difficulties in the  feeding  of  better producing  livestock such as cross bred lows in exploiting  their full  genetic potentiality for early growth, better  reproduction and higher milk production.

Livestock in the country, therefore, suffer widely from insufficient supply of nutrients. The unconventional agro-industrial by products and forest wastes may find a greater use as livestock feeds in coming years.

The nutritive value of tropical feeds and fodder is lower than those grown in temperate region. This situation does not allow cows to consume maximum amount feeds, nor to get feeds of minimum allowable digestibility. It is not possible to anticipate any remarkable improvement in the feed situation in the near future and also in the supply of high digestible ingredients like waste grains.

The digestibility of feed for meeting nutrient requirements of the cattle must bear relation to its intake capacity.

COST ESTIMATION

Plant Capacity                                    6 Ton/Day

Land & Building (1500 sq.mt.)          Rs. 2.21 Cr

Plant & Machinery                               Rs. 91 Lac

Working Capital for 2 Months          Rs. 1.79 Cr

Total Capital Investment                    Rs. 5.11 Cr

Rate of Return                                      47%

Break Even Point                                 43%


  • INTRODUCTION
  • RAW MATERIALS
  • PRODUCT DETAILS:
  • USES AND APPLICATION
  • PROPERTIES
  • SPECIFICATION OF CHOLINE CHLORIDE
  • MARKET OVERVIEW OF CHOLINE CHLORIDE
  • GLOBAL FEED MARKET
  • INDIAN ANIMAL FEED MARKET
  • INDIAN ANIMAL FEED MARKET STRUCTURE
  • ANIMAL FEED CONSUMPTION AND GROWTH IN INDIA
  • POULTRY FEEDING SYSTEM IN INDIA
  • STATE-WISE POULTRY FEED REQUIREMENT
  • MANUFACTURING PROCESS OF CHOLINE CHLORIDE FROM ETHYLENE OXIDE ROUTE
  • CHOLINE CHLORIDE (60%) POWDER (CORN COB BASED)
  • MASS BALANCE
  • BATCH SIZE: 1500 KGS
  • MASS BALANCE OF CHOLINE CHLORIDE (60%) POWDER
  • BASIS: 1000 KGS
  • PROCESS OF CHOLINE CHLORIDE POWDER (60%) PRECIPITATED SILICA BASED
  • MASS BALANCE
  • BASIS: 1000 KGS
  • PROCESS FLOW DIAGRAM
  • DETAILS OF CHOLINE CHLORIDE MANUFACTURE FROM HCL AND TMA
  • MANUFACTURING PROCESS OF CHOLINE CHLORIDE (CHOLINE HYDROXIDE AND HCL REACTION)
  • REACTION
  • PROCESS FLOW DIAGRAM
  • METHOD OF CHOLINE CHLORIDE MANUFACTURE
  • MINIMUM REQUIREMENT OF VARIOUS BREED/STRAIN (G/MT OF FEED)
  • MATERIAL SAFETY DATA SHEET FOR CHOLINE CHLORIDE
  • PRODUCT IDENTIFIERS:
  • HAZARDS IDENTIFICATION
  • CLASSIFICATION OF THE SUBSTANCE OR MIXTURE
  • LABEL ELEMENTS
  • OTHER HAZARDS
  • COMPOSITION/INFORMATION ON INGREDIENTS
  • SUBSTANCES
  • FIRST AID MEASURES
  • DESCRIPTION OF FIRST AID MEASURES
  • GENERAL ADVICE
  • IF INHALED
  • IN CASE OF SKIN CONTACT
  • IN CASE OF EYE CONTACT
  • IF SWALLOWED
  • MOST IMPORTANT SYMPTOMS AND EFFECTS, BOTH ACUTE AND DELAYED
  • FIREFIGHTING MEASURES
  • EXTINGUISHING MEDIA
  • SUITABLE EXTINGUISHING MEDIA
  • SPECIAL HAZARDS ARISING FROM THE SUBSTANCE OR MIXTURE
  • ADVICE FOR FIREFIGHTERS
  • ACCIDENTAL RELEASE MEASURES
  • PERSONAL PRECAUTIONS, PROTECTIVE EQUIPMENT AND EMERGENCY PROCEDURES
  • ENVIRONMENTAL PRECAUTIONS
  • METHODS AND MATERIALS FOR CONTAINMENT AND CLEANING UP
  • HANDLING AND STORAGE
  • PRECAUTIONS FOR SAFE HANDLING
  • CONDITIONS FOR SAFE STORAGE, INCLUDING ANY INCOMPATIBILITIES
  • EXPOSURE CONTROLS/PERSONAL PROTECTION
  • CONTROL PARAMETERS
  • EXPOSURE CONTROLS
  • APPROPRIATE ENGINEERING CONTROLS
  • PERSONAL PROTECTIVE EQUIPMENT
  • EYE/FACE PROTECTION
  • SKIN PROTECTION
  • BODY PROTECTION
  • RESPIRATORY PROTECTION
  • CONTROL OF ENVIRONMENTAL EXPOSURE
  • PHYSICAL AND CHEMICAL PROPERTIES
  • INFORMATION ON BASIC PHYSICAL AND CHEMICAL PROPERTIES
  • PRINCIPLES OF PLANT LAYOUT
  • MAJOR PROVISIONS IN ROAD PLANNING FOR MULTIPURPOSE SERVICE ARE:
  • PLANT LOCATION FACTORS
  • PRIMARY FACTORS
  • 1. RAW-MATERIAL SUPPLY:
  • 2. MARKETS:
  • 3. POWER AND FUEL SUPPLY:
  • 4. WATER SUPPLY:
  • 5. CLIMATE:
  • 6. TRANSPORTATION:
  • 7. WASTE DISPOSAL:
  • 8. LABOR:
  • 9. REGULATORY LAWS:
  • 10. TAXES:
  • 11. SITE CHARACTERISTICS:
  • 12. COMMUNITY FACTORS:
  • 13. VULNERABILITY TO WARTIME ATTACK:
  • 14. FLOOD AND FIRE CONTROL:
  • EXPLANATION OF TERMS USED IN THE PROJECT REPORT
  • 1. DEPRECIATION:
  • 2. FIXED ASSETS:
  • 3. WORKING CAPITAL:
  • 4. BREAK-EVEN POINT:
  • 5. OTHER FIXED EXPENSES:
  • 6. MARGIN MONEY:
  • 7. TOTAL LOAD:
  • 8. LAND AREA/MAN POWER RATIO:
  • PROJECT IMPLEMENTATION SCHEDULES
  • INTRODUCTION
  • PROJECT HANDLING
  • PROJECT SCHEDULING
  • PROJECT CONSTRUCTION SCHEDULE
  • TIME SCHEDULE
  • SUPPLIERS OF PLANT AND MACHINERY
  • SUPPLIERS OF MIXER/BLENDERS
  • SUPPLIERS OF PULVERIZERS
  • SUPPLIERS OF BAG FILLING AND SEALING MACHINES
  • SUPPLIERS OF WEIGHING MACHINE
  • SUPPLIERS OF RAW MATERIALS

APPENDIX – A:

01. PLANT ECONOMICS

02. LAND & BUILDING

03. PLANT AND MACHINERY

04. OTHER FIXED ASSESTS

05. FIXED CAPITAL

06. RAW MATERIAL

07. SALARY AND WAGES

08. UTILITIES AND OVERHEADS

09. TOTAL WORKING CAPITAL

10. TOTAL CAPITAL INVESTMENT

11. COST OF PRODUCTION

12. TURN OVER/ANNUM

13. BREAK EVEN POINT

14. RESOURCES FOR FINANCE

15. INSTALMENT PAYABLE IN 5 YEARS

16. DEPRECIATION CHART FOR 5 YEARS

17. PROFIT ANALYSIS FOR 5 YEARS

18. PROJECTED BALANCE SHEET FOR (5 YEARS)


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