Welcome to the world of pharmaceutical manufacturing, a realm where science, innovation, and precision converge to bring life-enhancing medications to people across the globe. "Complete Technology Handbook on Active Pharmaceutical Ingredients, Bulk Drugs & Pharmaceutical Salts Including Medical Products" is your gateway to understanding the intricate processes, technologies, and principles that underpin this critical industry.
This handbook is a comprehensive compendium, designed to guide you through the multifaceted landscape of pharmaceutical production. It delves into a myriad of topics, offering in-depth insights into the various stages of pharmaceutical manufacturing, from the formulation of active pharmaceutical ingredients (APIs) to the development of life-saving medical products.
Our journey begins with a foundational exploration of pharmaceutical manufacturing. This book unravels the components that constitute pharmaceutical drugs, providing a comprehensive overview of the industry's essentials. From the manufacture of APIs to an understanding of the pharmaceutical sector's broader landscape, we set the stage for an enlightening journey into the world of medicines. For those with the ambition to establish pharmaceutical manufacturing facilities, the book provides a roadmap. Here, you will find essential steps for setting up your pharmaceutical plant, including insights into the licenses required, documentation, and the crucial Goods and Service Tax (GST) registration process. We also explore the role of cutting-edge CNC machining in pharmaceutical manufacturing, underscoring the need for modern technology in this industry.
Tablets are a fundamental form of pharmaceuticals, and the book takes you on a journey into their composition, formulation, and manufacturing. We explore the ingredients and excipients that give tablets their identity, the equipment used in tablet manufacturing, and advances in tablet formulation technology. Discover the nuances of the tablet manufacturing process, including critical equipment such as tablet punching machines and the vital role of tablet compression. Tablet coating is an intricate process that improves the appearance, stability, and effectiveness of medications. In this book, we delve into various coating methods, recent technologies, and equipment used in the coating process. Our exploration includes vacuum film coating, offering you a holistic understanding of this critical aspect of tablet production.
Paracetamol, one of the world's most widely used pain relievers, takes center stage in this book. We begin with a thorough examination of its chemistry, pharmacokinetics, and physical properties. You'll gain insight into the synthesis of paracetamol and its presence on the pharmaceutical market. The book concludes with a detailed exploration of the tablet manufacturing process and the evaluation of these essential medications.
As you embark on this journey through the pages of our handbook, you'll gain a deeper appreciation for the complexities and importance of the pharmaceutical manufacturing industry. Whether you are a budding entrepreneur looking to start your own pharmaceutical venture, an industry enthusiast, or a professional seeking to deepen your knowledge, the information within these pages will serve as your compass.
The book contains chapters on Introduction, Start-up of Pharmaceutical Manufacturing, Various Types of Tablet and their Manufacturing Process, Tablet Coating Production Process, Paracetamol Tablet Production Technology, Metronidazole Tablet Manufacturing, Aspirin Manufacturing Production, IV Fluids Manufacturing, Ointment Manufacturing Technology, Liquid Glucose Technology, Surgical Cotton Manufacturing, Syrup Manufacturing Technology, Techniques for Making Pharmaceutically Acceptable Salts, Lotion Manufacturing Technology, Capsule Production Technology, How to Manufacture Active Pharmaceutical Ingredient (API), Details on Excipients and Active Pharmaceutical Ingredients, Good Manufacturing Practice Guidance for Active Pharmaceutical Ingredients, Active Pharmaceutical Ingredient (API) Chemicals, 237 Salts with their raw materials and manufacturing process, Plant Economics of Active Pharma Ingredients (API) [Azithromycin, Alpha Lipoic Acid, Pregablin, Naproxen, Ketoprofen], Plant Economics of Active Pharma Ingredients (API) (M-Bromo Anisole, Ethyl Triphenyl Phosphonium Bromide, Cinnamylaldehyde, MPhenoxybenzyl Alcohol, Benzyl Alcohol), Plant Economics of Ayush Pharmacy, Plant Economics of Dextrose Saline (I.V. Fluid) (FFS Technology) (Cap: 60,000 Bottles/Day), Plant Economics of Empty Hard Gelatine Capsules (Production Capacity: 1,60,000 nos./hour), Plant Economics of Isopropyl Alcohol (Medical Alcohol), Plant Economics of Oncology Manufacturing, Plant Economics of Pharma Grade Ferrous Sulphate Heptahydrate, Plant Economics of Pharmaceutical Unit (Tablet, Capsules, Syrups, Ointments, Lotion).
Chapter 1
Introduction
- Components of Drugs
- Manufacture of APIs
- APIs and Other Medication Components
- The Pharmaceutical Sector
Chapter 2
Start-up of Pharmaceutical Manufacturing
- Steps to Set Up a Pharmaceutical Manufacturing Plant in India
- Set up the Machinery & the Plant
- License Required to Start a Pharmaceutical Business in India
- Retail Drug License
- Manufacturing Drug License
- Loan Drug License in India
- Requirement for Obtaining Drug License
- Documents Required for Obtaining Drug License
- Goods and Service Tax (GST) Registration
- CNC machining for the pharmaceutical industry
Chapter 3
Various Types of Tablet and their Manufacturing Process
- Ingredients or excipients used in Tablets
- Types
- Tabletting formulations
- Manufacture of the tablets
- Tablet compaction simulator
- Tablet coating
- Pill-splitters
- Tablet Making Process
- Types of Equipment Used in Tablet Manufacturing
- Tablet manufacturing process
- Tablet punching machine
- Compression and consolidation in tablet manufacturing
- Volume reduction mechanism during compression
- Tablet Defects
- Packaging
- Recent advances in tablet formulation technology
- Marketed scope in tablet Compression technology
- Mottling
Chapter 4
Tablet Coating Production Process
- Introduction
- Different Methods of Coating
- Recent Technologies in Coating
- Defects of coated tablets
- Equipment
- Vacuum Film Coating
Chapter 5
Paracetamol Tablet Production Technology
- Introduction
- Chemistry
- Prostaglandin inhibition
- Serotoninergic pathway activation
- Endocannabinoid enhancement
- Pharmacokinetics
- Peripartum drug handling
- Drug interactions
- Physical properties
- Formation of Paracetamol
- Types of Paracetamol
- Paracetamol with other medicines
- Synthesis of Paracetamol
- Paracetamol on the Pharmaceutical Market
- Process of Tablet Manufacturing
- Evaluation of tablets
Chapter 6
Metronidazole Tablet Manufacturing
- Medical Uses
- Materials and Methods
- Preparation of tablets
- Wet granulation
- Dry granulation
- Direct compression
- Preparation of capsules
- Tablet and capsule evaluation
Chapter 7
Aspirin Manufacturing
- Introduction
- Chemical properties
- Synthesis
- Physical properties
- Mechanism of action
- Uses
- Raw Materials
- The Manufacturing Process
Chapter 8
IV Fluids Manufacturing
- Introduction
- Types of IV Fluids
- Intravenous fluids uses
- Design
- Raw Materials
- The Manufacturing Process
Chapter 9
Ointment Manufacturing Technology
- Types of Ointments
- Types of ointment bases
- Selection of ointment bases
- Ointment Applications
- Ointment Prepared by Trituration
- Ointment Preparation by Chemical Reaction
- Preparation of Ointments by Emulsification
- Properties of the Ointment Manufacturing Plant
- Working Principle of Ointment Manufacturing Plant
Chapter 10
Liquid Glucose Technology
- Structure of Glucose – C6H12O6
- Features of Liquid Glucose
- Applications of Liquid Glucose Rice
- Specification of Food Grade Liquid Glucose
- Interferences Corrected for by Strip Meter
- Glucose Formula
- Structure of Glucose
- Uses of Glucose
- Structure formula of Fructose
- Fructose and fermentation
- Anomeric Forms of Glucose
- Liquid glucose manufacturing process
Chapter 11
Surgical Cotton Manufacturing
- Product and its application
- Machinery Needed
- Raw material required to make surgical cotton
- Licenses and Registration
- Surgical cotton Manufacturing Process
- Surgical Cotton Making Machine
Chapter 12
Syrup Manufacturing Technology
- Preservation of Syrups
- Calculation of the Amount Added
- Sugars Used in Preparing Syrups Sucrose:
- Simple Syrup (Sirupus Simplex)
- Percolation Method
- Storage
- Incompatibilities
- Artificial syrups. Non nutritive syrups:
- Saccharin Sodium: (Sucaryl Sodium)
- Potassium chloride syrup
- Syrup Process Description
- Components of the syrup room
Chapter 13
Techniques for Making Pharmaceutically Acceptable Salts
- Introduction
- Why is Some Drugs Available in Salt Form?
- Salt-Selection Strategy
- Patent aspects of salt forms
- Regulatory aspects of salt forms
- Physicochemical Aspects of Salts
- Biopharmaceutical Aspects
Chapter 14
Lotion Manufacturing Technology
- Chemistry of Lotion
- Main Chemicals, Compounds, Components
- Chemistry’s Role
- Mechanism of action
- Advantages of using topical drugs
- Aloevera and Almond Formulation
- Formulation of Lotion and Cream
- Evaluation of Lotion and Cream
- The types
- Synthesis of Lotion
- Formula
- Process of Lotion Manufacturing
- Lotion Making Machine Mixers
- Cosmetic cream filler
Chapter 15
Capsule Production Technology
- Advantages of Capsules
- Raw Materials for Capsules
- The Manufacturing Process
- Hard Gelatin Capsule Step by Step Manufacturing Process
- Hard gelatin capsule Manufacturing Process
- Liquids in Hard Gelatin Capsules
- Industrial scale filling
- Types of excipients used in powder-filled capsules
- Cleaning and Packaging
- Difficulties in filling capsules
- Packaging and storage of capsules
- Capsule Administration
- Special types of hard gelatin capsules
- Liquid filled hard gelatin capsules
- Capsules for packing of ophthalmic ointments
- Recent updates in Capsule technology
Chapter 16
How to Manufacture Active Pharmaceutical Ingredient (API)
- Examples of Active Pharmaceutical Ingredients
- Characteristics of API Production
- GMP API Pharmaceutical Manufacturing Services
- Manufacturing API from a natural, synthetic, or semi-synthetic base
- Follow GMP standards for your API making equipment
- Classification of API must be clearly displayed on your product label
- HPAPI manufacturing requires expert containment solutions
- Preparing the API Manufacturing Process for Launch
- Process Validation
- Step Into the Spotlight: Early Filing with the FDA
- Types of Active Pharmaceutical Ingredient
- Active Pharmaceutical Ingredient Manufacturing Process
- Active Pharmaceutical Ingredients – Regulation and Inspection
- API Production and Demand
- Active Pharmaceutical Ingredients (API) Industry Segmentation
- Production Process
- Production characteristics
- Regulations
Chapter 17
Details on Excipients and Active Pharmaceutical Ingredients
- Introduction
- Excipients
Chapter 18
Good Manufacturing Practice Guidance for Active Pharmaceutical Ingredients
- Introduction
- Quality Management
- Personnel
- Buildings and Facilities
- Process Equipment
- Documentation and Records
- Materials Management
- Production and In-process Controls
- Packaging and identification labeling of apis and intermediates
- Storage and Distribution
- Laboratory Controls
- Validation
- Change Control
- Rejection and Re-use of Materials
- Complaints and Recalls
- Contract manufacturers (including laboratories)
- Agents, Brokers, Traders, Distributors, Repackers, and Relabellers
- Specific Guidance for APIs Manufactured by Cell Culture/Fermentation
- APIs For Use in Clinical Trials
Chapter 19
Active Pharmaceutical Ingredient (API) Chemicals
- Introduction
- Environmental issues associated with the production of API chemicals through chemical route
- Method of biomasses conversion in APIs synthesis
- Some important types of API chemicals
- Challenges and solutions to overcome the production of APIs chemicals through biotechnological route
- Future prospect of biomass to active pharmaceutical ingredient chemicals
Chapter 20
Acebutolol
- Raw Materials
- Manufacturing Process
Chapter 21
Acemetacin
- Raw Materials
- Manufacturing Process
Chapter 22
Acetaminophen
- Raw Materials
- Manufacturing Process
Chapter 23
Acetazolamide
- Raw Materials
- Manufacturing Process
Chapter 24
Acetophenazine Dimaleate
- Raw Materials
- Manufacturing Process
Chapter 25
Acetyldigitoxin
- Raw Materials
- Manufacturing Process
Chapter 26
Aclarubicin
- Raw Materials
- Manufacturing Process
Chapter 27
Acyclovir
- Raw Materials
- Manufacturing Process
Chapter 28
Afloqualone
- Raw Materiels
- Manufacturing Process
Chapter 29
Alcofenac
- Raw Materials
- Manufacturing Process
Chapter 30
Alcuronium Chloride
- Raw Materials
- Manufacturing Process
Chapter 31
Alfentanil Hydrochloride
- Raw Materials
- Manufacturing Process
Chapter 32
Alprazolam
- Raw Materials
- Manufacturing Process
Chapter 33
Aluminum Nicotinate
- Raw Materials
- Manufacturing Process
Chapter 34
Amikacin
- Raw Materials
- Manufacturing Process
Chapter 35
Amiodarone Hydrochloride
- Raw Materials
- Manufacturing Process
Chapter 36
Amitriptyline Oxide
- Raw Materials
- Manufacturing Process
Chapter 37
Amoxicillin
- Raw Materials
- Manufacturing Process
Chapter 38
Amphetamine Phosphate
- Raw Materials
- Manufacturing Prosess
Chapter 39
Amphomycin Calcium
- Raw Materials
- Manufacturing Process
Chapter 40
Amphotericin B
- Raw Materials
- Manufacturing Process
Chapter 41
Ampicillin
- Raw Materials
- Manufacturing Process
Chapter 42
Arginine Glutamate
- Raw Materials
- Manufacturing Process
Chapter 43
Aspartame
- Raw Materials
- Manufacturing Process
Chapter 44
Aspirin
- Raw Materials
- Manufacturing Process
Chapter 45
Atracurium Besylate
- Raw Materials
- Manufacturing Process
Chapter 46
Azathioprine
- Raw Materials
- Manufacturing Process
Chapter 47
Baclofen
- Raw Materials
- Manufacturing Process
Chapter 48
Batroxobin
- Raw Materials
- Manufacturing Process
Chapter 49
Benactyzine Hydrochloride
- Raw Materials
- Manufacturing Process
Chapter 50
Bendroflumethiazide
- Raw Materials
- Manufacturing Process
Chapter 51
Benfurodil Henisuccinate
- Raw Materials
- Manufacturing Process
Chapter 52
Benperidol
- Raw Materials
- Manufacturing Process
Chapter 53
Benproperine
- Raw Materials
- Manufacturing Process
Chapter 54
Bentiromide
- Raw Materials
- Manufacturing Process
Chapter 55
Benzonatate
- Raw Materials
- Manufacturing Process
Chapter 56
Benztropine Mesylate
- Raw Materials
- Manufacturing Process
Chapter 57
Betamethasone Benzoate
- Raw Materials
- Manufacturing Process
Chapter 58
Betaxolol Hydrochloride
- Raw Materials
- Manufacturing Process
Chapter 59
Betazole
- Raw Materials
- Manufacturing Process
Chapter 60
Bietaserpine
- Raw Materials
- Manufacturing Process
Chapter 61
Bisacodyl
- Raw Materials
- Manufacturing Process
Chapter 62
Bromelain
- Raw Materials
- Manufacturing Process
Chapter 63
Bromocriptine
- Raw Materials
- Manufacturing Process
Chapter 64
Bromopride
- Raw Materials
- Manufacturing Process
Chapter 65
Buformin HCL
- Raw Materials
- Manufacturing Process
Chapter 66
Bupivacaine
- Raw Materials
- Manufacturing Process
Chapter 67
Butamirate Citrate
- Raw Materials
- Manufacturing Process
Chapter 68
Cafaminol
- Raw Materials
- Manufacturing Process
Chapter 69
Calcitriol
- Raw Materials
- Manufacturing Process
Chapter 70
Camazepam
- Raw Materials
- Manufacturing Process
Chapter 71
Captodiamine
- Raw Materials
- Manufacturing Process
Chapter 72
Carazolol
- Raw Materials
- Manufacturing Process
Chapter 73
Carbidopa
- Raw Materials
- Manufacturing Process
Chapter 74
Carbinoxamine Maleate
- Raw Materials
- Manufacturing Process
Chapter 75
Carbomycin
- Raw Materials
- Manufacturing Process
Chapter 76
Caroxazone
- Raw Materials
- Manufacturing Process
Chapter 77
Carphenazine Maleate
- Raw Materials
- Manufacturing Process
Chapter 78
Cefotaxime Sodium
- Raw Materials
- Manufacturing Process
Chapter 79
Ceftazidime
- Raw Materials
- Manufacturing Process
Chapter 80
Cephalothin Sodium
- Raw Materials
- Manufacturing Process
Chapter 81
Chenodiol
- Raw Materials
- Manufacturing Process
Chapter 82
Chloral Betaine
- Raw Materials
- Manufacturing Process
Chapter 83
Chloroquine Phosphate
- Raw Materials
- Manufacturing Process
Chapter 84
Chlorotrianisene
- Raw Materials
- Manufacturing Process
Chapter 85
Chlorphenesin Carbamate
- Raw Materials
- Manufacturing Process
Chapter 86
Cimetidine
- Raw Materials
- Manufacturing Process
Chapter 87
Clavulanic Acid
- Raw Materials
- Manufacturing Process
Chapter 88
Clindamycin Hydrochloride
- Raw Materials
- Manufacturing Process
Chapter 89
Clobetasol
- Raw Materials
- Manufacturing Process
Chapter 90
Clofibrate
- Raw Materials
- Manufacturing Process
Chapter 91
Clomipramine
- Raw Materials
- Manufacturing Process
Chapter 92
Cortisone Acetate
- Raw Materials
- Manufacturing Process
Chapter 93
Cyclobenzaprime
- Raw Materials
- Manufacturing Process
Chapter 94
Cyclobutyrol
- Raw Materials
- Manufacturing Process
Chapter 95
Cyclofenil
- Raw Materials
- Manufacturing Process
Chapter 96
Cycloserine
- Raw Materials
- Manufacturing Process
Chapter 97
Dactinomycin
- Raw Materials
- Manufacturing Process
Chapter 98
Daunorubicin
- Raw Materials
- Manufacturing Process
Chapter 99
Deanol Acetamidobenzoate
- Raw Materials
- Manufacturing Process
Chapter 100
Dextran 40
- Raw Materials
- Manufacturing Process
Chapter 101
Dextroamphetamine Sulfate
- Raw Materials
- Manufacturing Process
Chapter 102
Diazepam
- Raw Materials
- Manufacturing Process
Chapter 103
Diclofenac Sodium
- Raw Materials
- Manufacturing Process
Chapter 104
Diethylstilbestrol
- Raw Materials
- Manufacturing Process
Chapter 105
Dihydrostreptomycin Sulfate
- Raw Materials
- Manufacturing Process
Chapter 106
Dihydrotachysterol
- Raw Materials
- Manufacturing Process
Chapter 107
Dimercaprol
- Raw Materials
- Manufacturing Process
Chapter 108
Dimethicone
- Raw Materials
- Manufacturing Process
Chapter 109
Diosmin
- Raw Materials
- Manufacturing Process
Chapter 110
Diphenadione
- Raw Materials
- Manufacturing Process
Chapter 111
Dipyridamole
- Raw Materials
- Manufacturing Process
Chapter 112
Disulfiram
- Raw Materials
- Manufacturing Process
Chapter 113
Docusate Calcium
- Raw Materials
- Manufacturing Process
Chapter 114
Doxapram Hydrochloride
- Raw Materials
- Manufacturing Process
Chapter 115
Doxorubicin
- Raw Materials
- Manufacturing Process
Chapter 116
Dromostanolone Propionate
- Raw Materials
- Manufacturing Process
Chapter 117
Dydrogesterone
- Raw Materials
- Manufacturing Process
Chapter 118
Edetate Disodium
- Raw Materials
- Manufacturing Process
Chapter 119
Edrophonium Chloride
- Raw Materials
- Manufacturing Process
Chapter 120
Erythromycin
- Raw Materials
- Manufacturing Process .495
Chapter 121
Estradiol Cypionate
- Raw Materials
- Manufacturing Process
Chapter 122
Estramustine Phosphate
- Raw Materials
- Manufacturing Process
Chapter 123
Etidronate Disodium
- Raw Materials
- Manufacturing Process
Chapter 124
Fazidinium Bromide
- Raw Materials
- Manufacturing Process
Chapter 125
Fenipentol
- Raw Materials
- Manufacturing Process
Chapter 126
Fentanyl
- Raw Materials
- Manufacturing Process
Chapter 127
Ferrocholinate
- Raw Materials
- Manufacturing Process
Chapter 128
Floxacillin
- Raw Materials
- Manufacturing Process
Chapter 129
Flubendazole
- Raw Materials
- Manufacturing Process
Chapter 130
Flunitrazepam
- Raw Materials
- Manufacturing Process
Chapter 131
Fluorouracil
- Raw Materials
- Manufacturing Process
Chapter 132
Folic Acid
- Raw Materials
- Manufacturing Process
Chapter 133
Fomocaine
- Raw Materials
- Manufacturing Process
Chapter 134
Fosfomycin
- Raw Materials
- Manufacturing Process
Chapter 135
Fructose
- Raw Materials
- Manufacturing Process
Chapter 136
Furaltadone
- Raw Materials
- Manufacturing Process
Chapter 137
Gallamine Triethiodide
- Raw Materials
- Manufacturing Process
Chapter 138
Gentamicin Sulfate
- Raw Materials
- Manufacturing Process
Chapter 139
Gliclazide
- Raw Materials
- Manufacturing Process
Chapter 140
Glipizide
- Raw Materials
- Manufacturing Process
Chapter 141
Glucagon
- Raw Materials
- Manufacturing Process
Chapter 142
Glymidine
- Raw Materials
- Manufacturing Process
Chapter 143
Gramicidin
- Raw Materials
- Manufacturing Process
Chapter 144
Guanfacine
- Raw Materials
- Manufacturing Process
Chapter 145
Haloperidol
- Raw Materials
- Manufacturing Process
Chapter 146
Heparin
- Raw Materials
- Manufacturing Process
Chapter 147
Hexestrol
- Raw Materials
- Raw Materials
Chapter 148
Homofenazine
- Raw Materials
- Manufacturing Process
Chapter 149
Hydrochlorothiazide
- Raw Materials
- Manufacturing Process
Chapter 150
Hydroxychloroquine Sulfate
- Raw Materials
- Manufacturing Process
Chapter 151
Hydroxystilbamidine Isethionate
- Raw Materials
- Manufacturing Process
Chapter 152
Hydroxyurea
- Raw Materials
- Manufacturing Process
Chapter 153
Ibuprofen
- Raw Materials
- Manufacturing Process
Chapter 154
Idoxuridine
- Raw Materials
- Manufacturing Process
Chapter 155
Ifenprodil Tartrate
- Raw Materials
- Manufacturing Process
Chapter 156
Imipramine Hydrochloride
- Raw Materials
- Manufacturing Process
Chapter 157
Improsulfan Tosylate
- Raw Materials
- Manufacturing Process
Chapter 158
Indenolol
- Raw Materials
- Manufacturing Process
Chapter 159
Inositol
- Raw Materials
- Manufacturing Process
Chapter 160
Insulin
- Raw Materials
- Manufacturing Process
Chapter 161
Iodamide
- Raw Materials
- Manufacturing Process
Chapter 162
Isaxonine Phosphate
- Raw Materials
- Manufacturing Process
Chapter 163
Kanamycin Sulfate
- Raw Materials
- Manufacturing Process
Chapter 164
Kebuzone
- Raw Materials
- Manufacturing Process
Chapter 165
Ketazolam
- Raw Materials
- Manufacturing Process
Chapter 166
Ketoprofen
- Raw Materials
- Manufacturing Process
Chapter 167
Ketotifen
- Raw Materials
- Manufacturing Process
Chapter 168
Lactulose
- Raw Materials
- Manufacturing Process
Chapter 169
Levodopa
- Raw Materials
- Manufacturing Process
Chapter 170
Lidocaine
- Raw Materials
- Manufacturing Process
Chapter 171
Loperamide Hydrochloride
- Raw Materials
- Manufacturing Process
Chapter 172
Loxapine
- Raw Materials
- Manufacturing Process
Chapter 173
Magaldrate
- Raw Materials
- Manufacturing Process
Chapter 174
Maltose
- Raw Materials
- Manufacturing Process
Chapter 175
Mannitol
- Raw Materials
- Manufacturing Process
Chapter 176
Meclofenamic Acid
- Raw Materials
- Manufacturing Process
Chapter 177
Medrogestone
- Raw Materials
- Manufacturing Process
Chapter 178
Mefenamic Acid
- Raw Materials
- Manufacturing Process
Chapter 179
Megestrol Acetate
- Raw Materials
- Manufacturing Process
Chapter 180
Melphalan
- Raw Materials
- Manufacturing Process
Chapter 181
Mercaptopurine
- Raw Materials
- Manufacturing Process
Chapter 182
Mestranol
- Raw Materials
- Manufacturing Process
Chapter 183
Methacycline
- Raw Materials
- Manufacturing Process
Chapter 184
Methysergide Maleate
- Raw Materials
- Manufacturing Process
Chapter 185
Metrizoic Acid
- Raw Materials
- Manufacturing Process
Chapter 186
Metyrapone
- Raw Materials
- Manufacturing Process
Chapter 187
Mexenone
- Raw Materials
- Manufacturing Process
Chapter 188
Midecamycin
- Raw Materials
- Manufacturing Process
Chapter 189
Mitobronitol
- Raw Materials
- Manufacturing Process
Chapter 190
Mitomycin
- Raw Materials
- Manufacturing Process
Chapter 191
Muzolimine
- Raw Materials
- Manufacturing Process
Chapter 192
Nalidixic Acid
- Raw Materials
- Manufacturing Process
Chapter 193
Naloxone
- Raw Materials
- Manufacturing Process
Chapter 194
Nandrolone Decanoate
- Raw Materials
- Manufacturing Process
Chapter 195
Naproxen
- Raw Materials
- Manufacturing Process
Chapter 196
Nefopam Hydrochloride
- Raw Materials
- Manufacturing Process
Chapter 197
Niaprazine
- Raw Materials
- Manufacturing Process
Chapter 198
Nicomol
- Raw Materials
- Manufacturing Process
Chapter 199
Nimetazepam
- Raw Materials
- Manufacturing Process
Chapter 200
Nitrofurantoin
- Raw Materials
- Manufacturing Process
Chapter 201
Novobiocin
- Raw Materials
- Manufacturing Process
Chapter 202
Octopamine Hydrochloride
- Raw Materials
- Manufacturing Process
Chapter 203
Oleandomycin
- Raw Materials
- Manufacturing Process
Chapter 204
Orazamide
- Raw Materials
- Manufacturing Process
Chapter 205
Orgotein
- Raw Materials
- Manufacturing Process
Chapter 206
Oxacillin Sodium
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